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Search Results for " folate receptor "

Targets

13

Compounds

17

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T76766 Mirvetuximab M9346A Antifolate
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form anti...
T76720 Farletuzumab MORAb-003 Antifolate
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Far...
T82378 Folate-MS432 PROTACs
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.
T68232 Epofolate
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th...
T39757 EC2629 EC2629
EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent.
T38490 ONX 0801 trisodium Idetrexedtrisodium,BGC 945 trisodium,CB300945trisodium
ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.
T29434 4-Desacetylvinblastine hydrazide DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide
Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.
T12635L Plevitrexed BGC9331,ZD 9331 Others
Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric ca...
T69268 BGC-638
BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors.
T19304 EC-17 disodium salt Others
EC-17 (disodium salt), a folate receptor alpha (FRα) targeting contrast agent, exhibits fluorescent properties within the visible light spectrum, characterized by peak excitation and emission wavelengths of 470/520 nm, r...
T13672 EC0489 Others
EC0489, Small molecule-drug conjugate (SMDC) ,a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor.
T77825 Mirvetuximab soravtansine IMGN853
Mirvetuximab soravtansine (IMGN853), an antibody-drug conjugate (ADC), integrates the cytotoxic agent DM4 with the humanized monoclonal antibody M9346A through a covalent bond. This compound targets folate receptor 1 (FO...
T77908 Farletuzumab ecteribulin MORAb-202
Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-06022 FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293 Cells
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is A0A2K5UR19&NP_001181576.1.
TMPY-01815 FOLR1 Protein, Human, Recombinant (His) Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A0A024R5H1.
TMPJ-00147 FOLR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328.
TMPY-01803 FOLR1 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
FOLR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P35846.
TMPY-01280 FOLR2 Protein, Human, Recombinant (His) Human HEK293 Cells
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ...
TMPY-02417 FOLR1 Protein, Canine, Recombinant (hFc) Canine HEK293 Cells
FOLR1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is A0A8C0Z2T7.
TMPY-00622 FOLR1 Protein, Canine, Recombinant (His) Canine HEK293 Cells
FOLR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0A8C0Z2T7.
TMPY-06928 FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.11 kDa and the accession number is NP_057937.1.
TMPY-04128 FOLR1 Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
FOLR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the accession number is G3V8M6.
TMPY-00543 FOLR1 Protein, Rat, Recombinant (His) Rat HEK293 Cells
FOLR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is G3V8M6.
TMPJ-00148 FOLR1 Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60.
TMPY-06929 FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.83 kDa and the accession number is NP_057937.1.
TMPK-00878 FOLR3 Protein, Human, Recombinant (His) Human HEK293 Cells
Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures.
TMPK-00150 FOLR1 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required ...
TMPK-01171 FOLR4/Juno Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Ju...
TMPK-00585 FOLR4/Juno Protein, Human, Recombinant (His) Human HEK293 Cells
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Ju...
TMPJ-01299 RTBDN Protein, Human, Recombinant (His) Human HEK293 Cells
Human Retbindin is a 229 amino acid secreted protein that belongs to the folate receptor family. The gene that encodes retbindin exists as two alternatively spliced isoforms. Retbindin is first expressed in retina. It ma...
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06022
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (His)
TMPY-01815
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc)
TMPJ-00147
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Mouse, Recombinant (His)
TMPY-01803
Species: Mouse
Expression System: HEK293 Cells
FOLR2 Protein, Human, Recombinant (His)
TMPY-01280
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Canine, Recombinant (hFc)
TMPY-02417
Species: Canine
Expression System: HEK293 Cells
FOLR1 Protein, Canine, Recombinant (His)
TMPY-00622
Species: Canine
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06928
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Rat, Recombinant (hFc)
TMPY-04128
Species: Rat
Expression System: HEK293 Cells
FOLR1 Protein, Rat, Recombinant (His)
TMPY-00543
Species: Rat
Expression System: HEK293 Cells
FOLR1 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00148
Species: Rhesus
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06929
Species: Human
Expression System: HEK293 Cells
FOLR3 Protein, Human, Recombinant (His)
TMPK-00878
Species: Human
Expression System: HEK293 Cells
FOLR1 Protein, Human, Recombinant (His & Avi)
TMPK-00150
Species: Human
Expression System: HEK293 Cells
FOLR4/Juno Protein, Mouse, Recombinant (His)
TMPK-01171
Species: Mouse
Expression System: HEK293 Cells
FOLR4/Juno Protein, Human, Recombinant (His)
TMPK-00585
Species: Human
Expression System: HEK293 Cells
RTBDN Protein, Human, Recombinant (His)
TMPJ-01299
Species: Human
Expression System: HEK293 Cells
TargetMol