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Cat No. | Product Name | Synonyms | Targets |
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T76766 | Mirvetuximab | M9346A | Antifolate |
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form anti... | |||
T76720 | Farletuzumab | MORAb-003 | Antifolate |
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuzumab inhibits the growth of cells that overexpress FRα. Far... | |||
T82378 | Folate-MS432 | PROTACs | |
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways. | |||
T68232 | Epofolate | ||
Epofolate is folate receptor-targeting antimitotic agent with potential antineoplastic activity. Folate receptor-targeted epothilone BMS753493 contains an epothilone moiety linked to a single folate molecule. Mediated th... | |||
T39757 | EC2629 | EC2629 | |
EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent. | |||
T38490 | ONX 0801 trisodium | Idetrexedtrisodium,BGC 945 trisodium,CB300945trisodium | |
ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor. | |||
T29434 | 4-Desacetylvinblastine hydrazide | DAVLBH,Deacetylvinblastine hydrazide,Desacetylvinblastine hydrazide | |
Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent. | |||
T12635L | Plevitrexed | BGC9331,ZD 9331 | Others |
Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM). Plevitrexed is used for gastric ca... | |||
T69268 | BGC-638 | ||
BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors. | |||
T19304 | EC-17 disodium salt | Others | |
EC-17 (disodium salt), a folate receptor alpha (FRα) targeting contrast agent, exhibits fluorescent properties within the visible light spectrum, characterized by peak excitation and emission wavelengths of 470/520 nm, r... | |||
T13672 | EC0489 | Others | |
EC0489, Small molecule-drug conjugate (SMDC) ,a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (FR). Refractory or metastatic Tumor. | |||
T77825 | Mirvetuximab soravtansine | IMGN853 | |
Mirvetuximab soravtansine (IMGN853), an antibody-drug conjugate (ADC), integrates the cytotoxic agent DM4 with the humanized monoclonal antibody M9346A through a covalent bond. This compound targets folate receptor 1 (FO... | |||
T77908 | Farletuzumab ecteribulin | MORAb-202 | |
Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-... |
Cat No. | Product Name | Species | Expression System |
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TMPY-06022 | FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) | Cynomolgus,Rhesus | HEK293 Cells |
FOLR1 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is A0A2K5UR19&NP_001181576.1. | |||
TMPY-01815 | FOLR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A0A024R5H1. | |||
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPY-01803 | FOLR1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
FOLR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P35846. | |||
TMPY-01280 | FOLR2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant ... | |||
TMPY-02417 | FOLR1 Protein, Canine, Recombinant (hFc) | Canine | HEK293 Cells |
FOLR1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.7 kDa and the accession number is A0A8C0Z2T7. | |||
TMPY-00622 | FOLR1 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
FOLR1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0A8C0Z2T7. | |||
TMPY-06928 | FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 53.11 kDa and the accession number is NP_057937.1. | |||
TMPY-04128 | FOLR1 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
FOLR1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the accession number is G3V8M6. | |||
TMPY-00543 | FOLR1 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
FOLR1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is G3V8M6. | |||
TMPJ-00148 | FOLR1 Protein, Rhesus macaque, Recombinant (His) | Rhesus | HEK293 Cells |
FOLR1 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-38 kDa and the accession number is F7BP60. | |||
TMPY-06929 | FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.83 kDa and the accession number is NP_057937.1. | |||
TMPK-00878 | FOLR3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Folic acid and folate receptors (FOLRs) play an important role in the downregulation of homocysteine (Hcy), a risk factor of Alzheimer's disease, thrombosis, neuropsychiatric illness and fractures. | |||
TMPK-00150 | FOLR1 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required ... | |||
TMPK-01171 | FOLR4/Juno Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Ju... | |||
TMPK-00585 | FOLR4/Juno Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Izumo1 is the only essential sperm-egg fusion protein currently known on mammalian sperm, and its egg receptor (Juno; formerly Folr4) was recently discovered. Male knockout mice for Izumo1 and female knockout mice for Ju... | |||
TMPJ-01299 | RTBDN Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Human Retbindin is a 229 amino acid secreted protein that belongs to the folate receptor family. The gene that encodes retbindin exists as two alternatively spliced isoforms. Retbindin is first expressed in retina. It ma... |